Gene
igf1
- ID
- ZDB-GENE-010607-2
- Name
- insulin-like growth factor 1
- Symbol
- igf1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Exhibits insulin-like growth factor receptor binding activity. Involved in dorsal/ventral pattern formation and positive regulation of cell population proliferation. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in several diseases, including acne; artery disease (multiple); diabetes mellitus (multiple); myopia; and neurodegenerative disease (multiple). Is expressed in several structures, including digestive system; eye; female organism; musculature system; and solid lens vesicle. Orthologous to human IGF1 (insulin like growth factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 57 figures from 48 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu524 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Insulin-like growth factor I deficiency | 608747 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Insulin, conserved site | Insulin family | Insulin-like | Insulin-like growth factor | Insulin-like growth factor I | Insulin-like superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q90VV9
|
161 |
Interactions and Pathways
Plasmids
No data available