ZFIN ID: ZDB-GENE-010504-1
Gene Name: nuclear receptor subfamily 5, group A, member 1a
Gene Symbol: nr5a1a
Sequence Ontology ID : SO:0000704

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Previous Names: nr5a4 (2), SF1-A (1), ff1b (4)

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(Including Attributions)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits DNA binding activity and DNA-binding activity transcription factor activity; involved in several processes, including animal organ development, positive regulation of transcription by RNA  ...
GENE EXPRESSION
All Expression Data: 55 figures from 28 publications
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2008 [af198086]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
zf2083 Complex Unknown Unknown CRISPR
Targeting reagents:
PHENOTYPE
Data: Fig. 3 from Mazilu et al., 2010
Observed in:
DISEASE ASSOCIATED WITH nr5a1a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
46 XY gonadal dysgenesis 46XY sex reversal 3 612965
premature ovarian failure Adrenocortical insufficiency 612964
Premature ovarian failure 7 612964
spermatogenic failure 8 Spermatogenic failure 8 613957
46, XX sex reversal 4 617480
46, XX sex reversal 4 617480
DISEASE ASSOCIATED WITH nr5a1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process positive regulation of transcription by RNA polymerase II (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 19)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000536 (1)
  • InterPro:IPR001628 (1)
  • InterPro:IPR001723 (1)
  • InterPro:IPR013088 (1)
  • InterPro:IPR016355 (1)
  • InterPro:IPR035500 (1)
  • PROSITE:PS00031 (1)
  • PROSITE:PS51030 (1)
  • PROSITE:PS51843 (1)
  • Pfam:PF00104 (1)
  • Pfam:PF00105 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nr5a1a-201 (1) 2531
    nr5a1a-202 (1) 505
    nr5a1a-203 (1) 1345
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nr5a1a
    MARKER RELATIONSHIPS
    nr5a1aContained in: [BAC] CH73-176N22 (1) (order this), CH211-237H13 (1) (order this)
    nr5a1aEncodes: [EST] af198086 (2) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131794 (1) 2522bp
    Genomic GenBank:CR936370 (1) 114220bp
    Select Tool
    Polypeptide UniProtKB:F1QJG0 (1) 454aa
    Sequence Clusters UniGene:53400 (1)
    Sequence Information (all 15)
    OTHER nr5a1a GENE PAGES
  • Alliance (1)
  • Gene:83916 (1)
  • VEGA:OTTDARG00000020542 (1)
  • Ensembl(GRCz11):ENSDARG00000103176 (1)
  • ORTHOLOGY for nr5a1a (Chr: 8)
    CITATIONS (65)