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Gene

cry1a

ID
ZDB-GENE-010426-2
Name
cryptochrome circadian regulator 1a
Symbol
cry1a Nomenclature History
Previous Names
  • cry1a
  • cry1aa
  • zcry1a (1)
  • zgc:153885
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to enable DNA binding activity and FAD binding activity. Acts upstream of or within several processes, including entrainment of circadian clock; negative regulation of transcription, DNA-templated; and response to hydrogen peroxide. Located in nucleus. Part of transcription regulator complex. Is expressed in brain; eye; integument; and kidney. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome. Orthologous to human CRY1 (cryptochrome circadian regulator 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 15 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cry1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Delayed sleep phase disorder, susceptibility to} 614163
Associated With cry1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain
Domain IPR006050 DNA photolyase, N-terminal
Homologous_superfamily IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Homologous_superfamily IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily
Homologous_superfamily IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Cryptochrome/DNA photolyase, FAD-binding domain Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Cryptochrome/photolyase, N-terminal domain superfamily DNA photolyase, N-terminal Rossmann-like alpha/beta/alpha sandwich fold
UniProtKB:Q08BE4 619
UniProtKB:A4QN37 619
UniProtKB:Q9I917 556
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations