Gene

cldnb

ID
ZDB-GENE-010328-2
Name
claudin b
Symbol
cldnb Nomenclature History
Previous Names
  • cldn30c (1)
  • wu:fa66b05
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have structural molecule activity. Involved in neuromast development and regulation of sodium ion transport. Predicted to localize to bicellular tight junction; integral component of membrane; and plasma membrane. Human ortholog(s) of this gene implicated in ovarian cancer and pancreatic cancer. Is expressed in several structures, including EVL; digestive system; integument; pleuroperitoneal region; and sensory system. Orthologous to human CLDN4 (claudin 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
35 figures from 19 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Kwong et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cldnb Human Ortholog
No data available
Associated With cldnb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004031 PMP-22/EMP/MP20/Claudin superfamily
Family IPR006187 Claudin
Domain Details Per Protein
Protein Length Claudin PMP-22/EMP/MP20/Claudin superfamily
UniProtKB:Q90XR8 215
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cldnb polyclonal Rabbit
  • IHC
Covance
4
Ab2-cldnb polyclonal Rabbit
1
Ab3-cldnb polyclonal Rabbit
  • IHC
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations