ZFIN ID: ZDB-GENE-010202-2
Gene Name: mitogen-activated protein kinase 14a
Gene Symbol: mapk14a    Nomenclature History

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Previous Names: p38 (1), p38a (1), zp38a (1), etID18993.8 (1), fk28c03, hm:zeh1243, wu:fk28c03 (1), zeh1243

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Exhibits MAP kinase activity. Involved in several processes, including embryonic cleavage; p38MAPK cascade; and regulation of collateral sprouting in absence of injury. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including digestive system; immature eye; nervous system; otic vesicle; and pronephric duct. Orthologous to human MAPK14 (mitogen-activated protein kinase 14).
Genome Resources: Alliance (1),  Gene:65237 (1),  Ensembl(GRCz11):ENSDARG00000000857 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la029455Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45323 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-mapk14a N/A 2
    DISEASE ASSOCIATED WITH mapk14a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mapk14a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to UV (more)
    Cellular Component cytoplasm (more)
    Molecular Function MAP kinase activity (more)
    GO Terms (all 24)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mapk14a-201 (1)    Ensembl 2289
    ncRNA mapk14a-002 (1)    Ensembl 736
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mapk14a No data available
    MARKER RELATIONSHIPS
    mapk14a Contained in: [BAC] CH211-163L21 (1)
    mapk14a Encodes: [EST] fk28c03 (1), zeh1243
    [cDNA] MGC:55209 (1), MGC:191577 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131722 (1) 2287 nt
    Genomic GenBank:AL929282 (1) 131005 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8QE41 (1) 361 aa
    Sequence Information (all 24)
    ORTHOLOGY for mapk14a ( Chr: 8 )
    CITATIONS (55)