ZFIN Gene: six4b

ZFIN ID: ZDB-GENE-010201-1

ZFIN ID: ZDB-GENE-010201-1

Gene Name:

SIX homeobox 4b

Gene Symbol:

six4b

Sequence Ontology ID :

SO:0001217

Previous Names:

six4.1, six8, etID17314.20 (1), wu:fj32d01 (1)

Location:

Chr: 20 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in ...

GENE EXPRESSION
All Expression Data:	19 figures from 13 publications
Wild-type Stages, Structures:	Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
	ectoderm lateral plate mesoderm neurogenic field posterior region neurogenic field neurogenic placode olfactory epithelium otic vesicle preplacodal ectoderm unspecified
Curated Microarray Expression:	GEO (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
oz31	Small Deletion	Unknown	Unknown	CRISPR
sa14754	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa15756	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa23674	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

Targeting reagents:

CRISPR1-six4b (1)
CRISPR2-six4b (1)

PHENOTYPE No data available

DISEASE ASSOCIATED WITH six4b HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH six4b VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	regulation of transcription, DNA-templated (more)
Cellular Component	nucleus (more)
Molecular Function	DNA binding (more)

GO Terms (all 9)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR001356 (1) InterPro:IPR009057 (1) InterPro:IPR017970 (1) InterPro:IPR031701 (1)	PROSITE:PS00027 (1) PROSITE:PS50071 (1)	Pfam:PF00046 (1) Pfam:PF16878 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	six4b-201 (1)	2406	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM six4b

Tg(six4b:mCherry)

MARKER RELATIONSHIPS

six4b Contained in:	[BAC] DKEY-225H23 (1) (order this)
six4b Encodes:	[EST] fj32d01 (1) [cDNA] MGC:76807 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131717 (1)	2436 bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX649231 (1)	153569 bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q5TYZ4 (1)	615 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:80781 (1)

Sequence Information (all 20)

OTHER six4b GENE PAGES

Alliance (1)

Gene:65232 (1)

VEGA:OTTDARG00000004931 (1)

Ensembl(GRCz11):ENSDARG00000031983 (2)

ORTHOLOGY for six4b ( Chr: 20 )

CITATIONS (49)

{{control.fieldName}} Edit

Attributions

Add new Alias

Attributions for Alias: {{control.newAlias}}

Delete Alias: