Gene

six4b

ID

ZDB-GENE-010201-1

Name

SIX homeobox 4b

Symbol

six4b Nomenclature History

Previous Names

six4.1
six8
etID17314.20 (1)
wu:fj32d01 (1)

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to nucleus and transcription regulator complex. Is expressed in ectoderm; lateral plate mesoderm; neurogenic field; otic vesicle; and sensory system. Orthologous to human SIX4 (SIX homeobox 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

20 figures from 14 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With six4b Human Ortholog

No data available

Associated With six4b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR001356	Homeobox domain
Domain	IPR031701	Homeobox protein SIX1, N-terminal SD domain
Homologous_superfamily	IPR009057	Homeobox-like domain superfamily