ZFIN ID: ZDB-GENE-010131-7
Gene Name: trypsin
Gene Symbol: try
Previous Names: wu:fb57g08 (1), zgc:109701
Location: Chr: 16   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 101 figures from 55 publications
Directly Submitted Expression Data: 7 figures (2 images) from Thisse et al., 2004 [MGC:109701]
  11 figures (18 images) from Rauch et al., 2003 [fb60g08]
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Adult (90d-730d, breeding adult)
  exocrine cell, exocrine pancreas, gut, heart (all 11) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS

Allele Type Mutagen Suppliers
sa16247 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE
    Phenotype of Human Orthologue OMIM Phenotype ID
    Pancreatitis, hereditary 167800
    Trypsinogen deficiency 614044
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component extracellular space (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001254 (1)
  • InterPro:IPR001314 (1)
  • InterPro:IPR009003 (1)
  • InterPro:IPR018114 (1)
  • PROSITE:PS00134 (1)
  • PROSITE:PS00135 (1)
  • PROSITE:PS50240 (1)
  • Pfam:PF00089 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA try-001 (1) 871
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM try No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    try Contained in: [BAC] DKEYP-84F3 (1)
    try Encodes: [EST] fb57g08, fb60g08 (1) (order this)
    [cDNA] MGC:109701 (1) (order this), MGC:193019 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131708 (1) 845 bp
    Genomic GenBank:BX539313 (1) 215158 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q561Z7 (1) 247 aa
    Sequence Clusters UniGene:75547 (1)
    Sequence Information (all 25)
    OTHER try GENE PAGES
  • Gene:65223 (1)
  • VEGA:OTTDARG00000021061 (1)
  • Ensembl(Zv9):ENSDARG00000042993 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish try 16  
    Human PRSS1 7 (7q34)
  • OMIM:276000
  • Gene:5644
  • Orthology Details
    CITATIONS (91)