ZFIN ID: ZDB-GENE-010131-7
Gene Name: trypsin
Gene Symbol: try
Previous Names: wu:fb57g08 (1), zgc:109701
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 114 figures from 60 publications
Directly Submitted Expression Data: 7 figures (2 images) from Thisse et al., 2004 [MGC:109701]
  11 figures (18 images) from Rauch et al., 2003 [fb60g08]
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Adult (90d-730d, breeding adult)
  anatomical structure, endocrine pancreas, exocrine cell, exocrine pancreas (all 13) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa16247 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH try HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Trypsinogen deficiency 614044
    Pancreatitis, hereditary 167800
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process proteolysis (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001254 (1)
  • InterPro:IPR001314 (1)
  • InterPro:IPR009003 (1)
  • InterPro:IPR018114 (1)
  • InterPro:IPR033116 (1)
  • PROSITE:PS00134 (1)
  • PROSITE:PS00135 (1)
  • PROSITE:PS50240 (1)
  • Pfam:PF00089 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA try-001 (1) 871
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM try
    Tg(try:GFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    tryContained in: [BAC] DKEYP-84F3 (1)
    tryEncodes: [EST] fb57g08, fb60g08 (1) (order this)
    [cDNA] MGC:109701 (1) (order this), MGC:193019 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131708 (1) 876bp
    Genomic GenBank:BX539313 (1) 215158bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q561Z7 (1) 247aa
    Sequence Clusters UniGene:75547 (1)
    Sequence Information (all 28)
    OTHER try GENE PAGES 
  • Gene:65223 (1)
  • VEGA:OTTDARG00000021061 (1)
  • Ensembl(GRCz10):ENSDARG00000042993 (1)
  • ORTHOLOGY for try (Chr: 16) 
    Species Symbol Chromosome Accession # Evidence
    Human PRSS1 7
  • Gene:5644
  • OMIM:276000
  • HGNC:9475
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (102)