ZFIN ID: ZDB-GENE-010131-7
Gene Name: protease, serine 1
Gene Symbol: prss1
Sequence Ontology ID : SO:0000704

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Previous Names: try (1), wu:fb57g08 (1), zgc:109701

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 132 figures from 71 publications
Directly Submitted Expression Data: 7 figures (2 images) from Thisse et al., 2004 [MGC:109701]
  11 figures (18 images) from Rauch et al., 2003 [fb60g08]
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Adult (90d-730d, breeding adult)
  acinar cell, anatomical structure, endocrine pancreas, exocrine cell (all 15) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16247 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH prss1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Trypsinogen deficiency 614044
    Pancreatitis, hereditary 167800
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component extracellular space (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001254
  • InterPro:IPR001314
  • InterPro:IPR009003
  • InterPro:IPR018114
  • InterPro:IPR033116
  • PROSITE:PS00134
  • PROSITE:PS00135
  • PROSITE:PS50240
  • Pfam:PF00089
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA try-001 (1) 871
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM prss1
    Tg(prss1:GFP)
    MARKER RELATIONSHIPS
    prss1Contained in: [BAC] DKEYP-84F3 (1)
    prss1Encodes: [EST] fb57g08, fb60g08 (1) (order this)
    [cDNA] MGC:109701 (1) (order this), MGC:193019 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131708 (1) 876bp
    Genomic GenBank:BX539313 (1) 215158bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q561Z7 247aa
    Sequence Clusters UniGene:75547 (1)
    Sequence Information (all 27)
    OTHER prss1 GENE PAGES
  • Alliance (1)
  • Gene:65223 (1)
  • VEGA:OTTDARG00000021061 (1)
  • Ensembl(GRCz10):ENSDARG00000042993 (1)
  • ORTHOLOGY for prss1 (Chr: 16)
    CITATIONS (114)