ZFIN ID: ZDB-GENE-001212-8
Gene Name: ATPase Na+/K+ transporting subunit alpha 3b
Gene Symbol: atp1a3b    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: atp[a]3A (1), cb706 (1), fj35g11, wu:fj35g11, wu:fq14g09

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have sodium:potassium-exchanging ATPase activity. Involved in locomotory behavior and ventricular system development. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in alternating hemiplegia of childhood; bipolar disorder; dystonia 12; and epilepsy. Is expressed in nervous system; neural tube; pronephric duct; and skeletal system. Orthologous to human ATP1A3 (ATPase Na+/K+ transporting subunit alpha 3).
Genome Resources: Alliance (1),  Gene:64611 (1),  Ensembl(GRCz11):ENSDARG00000104139 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6413 Point Mutation Unknown Splice Site ENU
sa8659 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9603 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22768 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36052 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-atp1a3b N/A 1
    MO2-atp1a3b N/A 1
    DISEASE ASSOCIATED WITH atp1a3b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    alternating hemiplegia of childhood Alliance Alternating hemiplegia of childhood 2 614820
    dystonia 12 Alliance Dystonia-12 128235
    CAPOS syndrome 601338
    DISEASE ASSOCIATED WITH atp1a3b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process locomotory behavior (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA atp1a3b-201 (1)    Ensembl 4787
    atp1a3b-203 (1)    Ensembl 653
    ncRNA atp1a3b-003 (1)    Ensembl 659
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atp1a3b No data available
    MARKER RELATIONSHIPS
    atp1a3b Contained in: [BAC] RP71-8C9 (1)
    atp1a3b Encodes: [EST] cb706 (2) (order this), fj35g11 (1), fq14g09 (1) (order this)
    [cDNA] MGC:109873 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131685 (1) 4801 nt
    Genomic GenBank:CU462827 (1) 183104 nt
    Select Tool
    Polypeptide UniProtKB:Q4KMK4 (1) 1023 aa
    Sequence Information (all 19)
    ORTHOLOGY for atp1a3b ( Chr: 16 )
    CITATIONS (30)