ZFIN ID: ZDB-GENE-001212-2
Gene Name: ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 2
Gene Symbol: atp1a1a.2    Nomenclature History

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Previous Names: atp[a]1A2b (1), cb703 (1), zgc:110523

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have sodium:potassium-exchanging ATPase activity. Involved in semicircular canal morphogenesis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2DD. Is expressed in several structures, including immature eye; integument; intermediate mesoderm; nervous system; and yolk. Orthologous to human ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1).
Genome Resources: Alliance (1),  Gene:64613 (1),  Ensembl(GRCz11):ENSDARG00000007739 (2)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH atp1a1a.2 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease type 2DD Alliance Charcot-Marie-Tooth disease, axonal, type 2DD 618036
Hypomagnesemia, seizures, and mental retardation 2 618314
DISEASE ASSOCIATED WITH atp1a1a.2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process semicircular canal morphogenesis (more)
Cellular Component integral component of membrane (more)
Molecular Function ATP binding (more)
GO Terms (all 15)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA atp1a1a.2-201 (1)    Ensembl 3232
ncRNA atp1a1a.2-002 (1)    Ensembl 479
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM atp1a1a.2
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(atp1a1a.2:RFP) atp1a1a.2 RFP Danio rerio 1 3
MARKER RELATIONSHIPS
atp1a1a.2 Contained in: [BAC] DKEY-208K14 (1) (order this)
atp1a1a.2 Encodes: [EST] cb703 (2) (order this)
[cDNA] MGC:110523 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131687 (1) 3235 nt
Genomic GenBank:CU185242 (1) 180192 nt
Select Tool
Polypeptide UniProtKB:B8JKS9 (1) 1023 aa
Sequence Information (all 18)
ORTHOLOGY for atp1a1a.2 ( Chr: 1 )
CITATIONS (34)