Gene

arnt2

ID
ZDB-GENE-001207-3
Name
aryl-hydrocarbon receptor nuclear translocator 2
Symbol
arnt2 Nomenclature History
Previous Names
  • arnt2X (1)
  • zfARNT2 (1)
  • chunp6921
  • unm t30256
  • unm_t30256
  • zfARNT2a (1)
  • zfARNT2b (1)
  • zfARNT2c (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Exhibits DNA-binding transcription factor activity. Involved in several processes, including animal organ development; neuron differentiation; and response to hypoxia. Predicted to localize to aryl hydrocarbon receptor complex and nucleus. Is expressed in several structures, including gut; hatching gland; mandibular arch skeleton; nervous system; and vasculature. Orthologous to human ARNT2 (aryl hydrocarbon receptor nuclear translocator 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
21 figures from 11 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arnt2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Webb-Dattani syndrome 615926
Associated With arnt2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000014 PAS domain
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Domain IPR013655 PAS fold-3
Domain IPR013767 PAS fold
Family IPR001067 Nuclear translocator
Homologous_superfamily IPR035965 PAS domain superfamily
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Repeat IPR001610 PAC motif
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Nuclear translocator PAC motif PAS domain PAS domain superfamily PAS fold PAS fold-3
UniProtKB:A0A0R4ID51 722
UniProtKB:A0A0R4ILG9 737
UniProtKB:O42302 237
UniProtKB:Q9DG12 737
UniProtKB:Q98SK3 392
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-arnt2 monoclonal IgG1 Mouse
Affinity BioReagents (Thermo Fisher Scientific)
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations