ZFIN ID: ZDB-GENE-001201-1
Gene Name: vitellogenin 1
Gene Symbol: vtg1    Nomenclature History

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Previous Names: vg1, zfvg1 (1), zgc:109796

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Exhibits antioxidant activity. Involved in cellular response to estrogen stimulus; response to estradiol; and response to xenobiotic stimulus. Predicted to localize to integral component of membrane. Is expressed in several structures, including adipose tissue; atrium; liver; pleuroperitoneal region; and unfertilized egg.
Genome Resources: Alliance (1),  Gene:559475 (1),  Ensembl(GRCz11):ENSDARG00000092233 (1)
Note: vtg1-201 is a transcript described in ZDB-PUB-180609-20 and matches ENSDART00000078276 (Zv9) and corresponds to the partial cDNA clone with sequence BC094995.
GENE EXPRESSION
All Expression Data: 45 figures from 30 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa5972 Point Mutation Unknown Premature Stop ENU
sa12457 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37521 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37522 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39374 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-vtg
    1
    CRISPR2-vtg
    1
    CRISPR3-vtg
    1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH vtg1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH vtg1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to estrogen stimulus (more)
    Cellular Component integral component of membrane (more)
    Molecular Function antioxidant activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA vtg1-201 (1)    Ensembl 4415
    ncRNA vtg1-002 (1)    Ensembl 990
    vtg1-003 (1)    Ensembl 917
    Browsers: UCSCEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM vtg1
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    tg(vtg1:mcherry) vtg1 mCherry Danio rerio 1 2
    Tg(Xla.Vtga2-vtg1:EGFP) vtg1 EGFP Danio rerioXenopus laevis 1 2
    MARKER RELATIONSHIPS
    vtg1 Contained in: [BAC] RP71-23D18 (1)
    vtg1 Encodes: [cDNA] MGC:109796, MGC:174137 (1)
    vtg1 Has Artifact: [EST] fb63b05, fb63d05, fb64d12, fb65b06, fb67a10, fb68e07, fd55c06, fd55e03 (1), fd55g08
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001044897 (1) 4230 nt
    Genomic GenBank:BX539332 (1) 176625 nt
    Select Tool
    Polypeptide UniProtKB:Q1LWN2 (1) 1362 aa
    Sequence Information (all 44)
    ORTHOLOGY for vtg1 ( Chr: 22 )
    CITATIONS (301)