Gene

atoh7

ID
ZDB-GENE-000926-1
Name
atonal bHLH transcription factor 7
Symbol
atoh7 Nomenclature History
Previous Names
  • ath5 (1)
  • lak
  • lakritz
  • Zath5 (1)
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have DNA binding activity and protein dimerization activity. Involved in several processes, including positive regulation of neurogenesis; retina layer formation; and swimming behavior. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in persistent hyperplastic primary vitreous. Is expressed in eye and immature eye. Orthologous to human ATOH7 (atonal bHLH transcription factor 7).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
77 figures from 59 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
18 figures from 16 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atoh7 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
persistent hyperplastic primary vitreous Alliance Persistent hyperplastic primary vitreous, autosomal recessive 221900
Associated With atoh7 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain
UniProtKB:Q8AW52 134
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations