Gene

myf5

ID
ZDB-GENE-000616-6
Name
myogenic factor 5
Symbol
myf5 Nomenclature History
Previous Names
  • myf-5
  • cb641 (1)
  • zgc:110509
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including muscle organ development; neural crest cell development; and striated muscle cell development. Located in nucleolus and nucleoplasm. Is expressed in several structures, including mesoderm; musculature system; myoblast; pharyngeal arch; and post-vent region. Orthologous to human MYF5 (myogenic factor 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
97 figures from 60 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
10 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With myf5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Ophthalmoplegia, external, with rib and vertebral anomalies 618155
Associated With myf5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002546 Myogenic muscle-specific protein, N-terminal
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Domain IPR022032 Myogenic determination factor 5
Family IPR039704 Myogenic factor
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Myogenic determination factor 5 Myogenic factor Myogenic muscle-specific protein, N-terminal
UniProtKB:Q5CZP8 237
UniProtKB:Q9DE55 121
UniProtKB:Q5TZ22 237
UniProtKB:Q9DDW0 237
UniProtKB:Q9I9H3 237
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations