ZFIN ID: ZDB-GENE-000616-6
Gene Name: myogenic factor 5
Gene Symbol: myf5    Nomenclature History

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Previous Names: myf-5, cb641 (1), zgc:110509

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in mesoderm development; muscle organ development; and neural crest cell development. Localizes to nucleolus and nucleoplasm. Is expressed in several structures, including mesoderm; musculature system; myoblast; pharyngeal arch; and post-vent region. Orthologous to human MYF5 (myogenic factor 5).
Genome Resources: Alliance (1),  Gene:58097 (1),  Ensembl(GRCz11):ENSDARG00000007277 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu2022 Point Mutation Unknown Premature Stop ENU
sa26293 Point Mutation Unknown Premature Stop ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-myf5 N/A 8
MO3-myf5 N/A 11
MO4-myf5 N/A 1
MO5-myf5 N/A 1
MO6-myf5 N/A 3
DISEASE ASSOCIATED WITH myf5 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Ophthalmoplegia, external, with rib and vertebral anomalies 618155
DISEASE ASSOCIATED WITH myf5 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process muscle organ development (more)
Cellular Component nucleolus (more)
Molecular Function DNA binding (more)
GO Terms (all 22)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA myf5-202 (1)    Ensembl 1415
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM myf5
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(-2.4myf5:EGFP) myf5 EGFP Danio rerio 1 3
Tg(-10.0myf5:EGFP) myf5 EGFP Danio rerio 1 10
Tg(-80.0myf5:EGFP) myf5 EGFP Danio rerio 1 10
Tg(AITR-0.3myf5:EGFP) myf5 EGFP Danio rerio 1 2
Tg(AITR-3.0myf5:EGFP) myf5 EGFP Danio rerio 1 2
Tg(AITR-6.0myf5:EGFP) myf5 EGFP Danio rerio 1 2
Tg(AITR-10.0myf5:EGFP) myf5 EGFP Danio rerio 1 2
Tg(myf5:EGFP) myf5 EGFP Danio rerio 1 3
MARKER RELATIONSHIPS
myf5 Contained in: [BAC] CH211-91G3 (1)
myf5 Encodes: [EST] cb641 (1)
[cDNA] MGC:110509 (1), MGC:192249 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131576 (1) 1433 nt
Genomic GenBank:BX537156 (1) 117987 nt
Select Tool
Polypeptide UniProtKB:Q5CZP8 (1) 237 aa
Sequence Information (all 24)
ORTHOLOGY for myf5 ( Chr: 4 )
CITATIONS (145)