Gene

kat6b

ID
ZDB-GENE-000607-52
Name
K(lysine) acetyltransferase 6B
Symbol
kat6b Nomenclature History
Previous Names
  • id:ibd5103 (1)
  • si:dkey-24f15.3 (1)
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have histone acetyltransferase activity; histone binding activity; and transcription coregulator activity. Predicted to be involved in negative regulation of transcription, DNA-templated and positive regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin. Is expressed in forebrain. Human ortholog(s) of this gene implicated in bipolar disorder; blepharophimosis-intellectual disability syndrome, SBBYS type; breast cancer; and leiomyoma. Orthologous to human KAT6B (lysine acetyltransferase 6B).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from Kudoh et al., 2001
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kat6b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
blepharophimosis-intellectual disability syndrome, SBBYS type Alliance SBBYSS syndrome 603736
Genitopatellar syndrome 606170
Associated With kat6b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001965 Zinc finger, PHD-type
Domain IPR002717 Histone acetyltransferase domain, MYST-type
Domain IPR005818 Linker histone H1/H5, domain H15
Domain IPR019787 Zinc finger, PHD-finger
Domain IPR040706 MYST, zinc finger domain
Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR016181 Acyl-CoA N-acyltransferase
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Acyl-CoA N-acyltransferase Histone acetyltransferase domain, MYST-type Linker histone H1/H5, domain H15 MYST, zinc finger domain Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily Zinc finger, FYVE/PHD-type Zinc finger, PHD-finger Zinc finger, PHD-type Zinc finger, RING/FYVE/PHD-type
UniProtKB:A0A2R8RKV9 150
UniProtKB:A0A2R8QFJ9 325
UniProtKB:B7ZD47 646
UniProtKB:B7ZD46 1368
UniProtKB:F1R4F8 1037
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations