ZFIN ID: ZDB-GENE-000526-1
Gene Name: hes-related family bHLH transcription factor with YRPW motif 2
Gene Symbol: hey2
Sequence Ontology ID : SO:0000704

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Previous Names: gridlock (1), grl (1), Herp2 (1), zgc:136746 (1)

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(Including Attributions)
Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have several functions, including nucleic acid binding activity, regulation of cellular process, and transcription factor binding activity; involved in several processes, including Notch  ...
GENE EXPRESSION
All Expression Data: 54 figures from 44 publications
Directly Submitted Expression Data: 6 figures (19 images) from Thisse et al., 2005 [eu521]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hsc25 Small Deletion Unknown Unknown CRISPR
m145 Point Mutation Unknown Missense ENU
sa10785 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16273 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23783 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa29430 Point Mutation Unknown Premature Stop ENU
    vu59 Point Mutation Unknown Premature Stop ENU
    zf80 Point Mutation Unknown Missense ENU
    Targeting reagents:
    PHENOTYPE
    Data: 12 figures from 9 publications
    Observed in:
    DISEASE ASSOCIATED WITH hey2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hey2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process blood vessel development (more)
    Cellular Component nucleus (more)
    Molecular Function protein binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003650 (1)
  • InterPro:IPR011598 (1)
  • InterPro:IPR036638 (1)
  • PROSITE:PS50888 (1)
  • PROSITE:PS51054 (1)
  • Pfam:PF00010 (1)
  • Pfam:PF07527 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hey2-201 (1) 1816
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM hey2
    MARKER RELATIONSHIPS
    hey2Contained in: [BAC] CH211-172B22 (1) (order this)
    hey2Encodes: [EST] eu521 (1)
    [cDNA] MGC:136746 (1) (order this), MGC:194026 (1), MGC:194033 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131622 (1) 1898bp
    Genomic GenBank:CT573083 (1) 40018bp
    Select Tool
    Polypeptide UniProtKB:B3DGE6 (1) 324aa
    Sequence Clusters UniGene:81319 (1)
    Sequence Information (all 23)
    OTHER hey2 GENE PAGES
  • Alliance (1)
  • Gene:58146 (1)
  • VEGA:OTTDARG00000023298 (1)
  • Ensembl(GRCz11):ENSDARG00000013441 (2)
  • ORTHOLOGY for hey2 (Chr: 20)
    CITATIONS (133)