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ZIRC
ZFIN ID: ZDB-GENE-000511-7
Gene Name: MCL1 apoptosis regulator, BCL2 family member a
Gene Symbol: mcl1a
Sequence Ontology ID : SO:0000704

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Previous Names: zfMcl-1a, fb70a08, fb72f02, wu:fb70a08, wu:fb72f02 (1), zfMLP1 (1), zgc:109835

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(Including Attributions)
Location: Chr: 19 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits protein heterodimerization activity. Involved in several processes, including negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation  ...
GENE EXPRESSION
All Expression Data: 6 figures from 6 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:109835]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10132 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12089 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mcl1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mcl1a VIA EXPERIMENTAL MODELS No data available
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mcl1a-201 (1) 1409
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mcl1a No data available
    MARKER RELATIONSHIPS
    mcl1aContained in: [BAC] DKEYP-24A7 (1)
    mcl1aEncodes: [EST] fb70a08, fb72f02 (1)
    [cDNA] MGC:109835 (1) (order this), MGC:192271 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131599 (1) 1253bp
    Genomic GenBank:CR548627 (1) 146348bp
    Select Tool
    Polypeptide UniProtKB:Q1L8X3 (1) 255aa
    Sequence Clusters UniGene:33208 (1)
    Sequence Information (all 23)
    ORTHOLOGY for mcl1a (Chr: 19)
    CITATIONS (39)