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ZIRC
ZFIN ID: ZDB-GENE-000511-6
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Gene Name: BCL2 associated X, apoptosis regulator a
Gene Symbol: baxa
Sequence Ontology ID : SO:0000704

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Previous Names: bax, fj16e01, wu:fc50b10, wu:fj16e01 (1), zBax1 (1)

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Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have channel activity; protein heterodimerization activity; and protein homodimerization activity. Involved in positive regulation of cysteine-type endopeptidase activity involved in  ...
GENE EXPRESSION
All Expression Data: 39 figures from 34 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66309]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6041 Point Mutation Unknown Premature Stop ENU
sa14515 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH baxa HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acute lymphocytic leukemia T-cell acute lymphoblastic leukemia, somatic 613065
    colorectal cancer Colorectal cancer, somatic 114500
    DISEASE ASSOCIATED WITH baxa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of apoptotic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function channel activity (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002475 (1)
  • InterPro:IPR026298 (1)
  • InterPro:IPR036834 (1)
    		•
  • PROSITE:PS50062 (1)
    		•
  • Pfam:PF00452 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA baxa-002 (1) 676
    Select Tool
    baxa-003 (1) 734
    Select Tool
    mRNA baxa-201 (1) 1981
    Select Tool
    aberrant processed transcript baxa-203 (1) 861
    Select Tool
    mRNA baxa-204 (1) 1720
    Select Tool
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM baxa
    MARKER RELATIONSHIPS
    baxaContained in: [BAC] DKEY-260C8 (1) (order this)
    baxaEncodes: [EST] fc50b10, fj16e01 (1)
    [cDNA] MGC:66309 (1) (order this), MGC:192165 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131562 (1) 1960bp
    Select Tool
    Genomic GenBank:CR388062 (1) 153088bp
    Select Tool
    Polypeptide UniProtKB:I3ITC2 (1) 197aa
    Select Tool
    Sequence Clusters UniGene:78968 (1)
    Sequence Information (all 21)
    OTHER baxa GENE PAGES
  • Alliance (1)
  • Gene:58081 (1)
  • VEGA:OTTDARG00000027248 (1)
  • VEGA:OTTDARG00000037551 (1)
  • Ensembl(GRCz11):ENSDARG00000020623 (2)
    • ORTHOLOGY for baxa (Chr: 3)
    CITATIONS (184)