Gene

mbl2

ID
ZDB-GENE-000427-2
Name
mannose binding lectin 2
Symbol
mbl2 Nomenclature History
Previous Names
  • mbl (1)
  • collectin
  • etID42583.2 (1)
  • fb68b07
  • GalBL (1)
  • hbl3 (1)
  • MBL-like (1)
  • wu:fb68b07 (1)
  • zgc:109836
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have carbohydrate binding activity. Predicted to localize to collagen trimer. Is expressed in liver. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); bacterial infectious disease (multiple); fungal infectious disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to several human genes including MBL2 (mannose binding lectin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Wang et al., 2008
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mbl2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Chronic infections, due to MBL deficiency} 614372
Associated With mbl2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018378 C-type lectin, conserved site
Domain IPR001304 C-type lectin-like
Domain IPR033990 Collectin, C-type lectin-like domain
Homologous_superfamily IPR016186 C-type lectin-like/link domain superfamily
Homologous_superfamily IPR016187 C-type lectin fold
Repeat IPR008160 Collagen triple helix repeat
Domain Details Per Protein
Protein Length Collagen triple helix repeat Collectin, C-type lectin-like domain C-type lectin, conserved site C-type lectin fold C-type lectin-like C-type lectin-like/link domain superfamily
UniProtKB:Q504I3 251
UniProtKB:B7ZVV2 251
UniProtKB:Q9I9Q8 251
UniProtKB:A0A2R8PXW9 251
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations