ZFIN ID: ZDB-GENE-000412-1
Gene Name: brain-derived neurotrophic factor
Gene Symbol: bdnf
Sequence Ontology ID : SO:0000704

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Location: Chr: 7 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Predicted to have growth factor activity; involved in brain development, multicellular organismal response to stress, and nervous system development; predicted to localize to several cellular  ...
GENE EXPRESSION
All Expression Data: 52 figures from 19 publications
Directly Submitted Expression Data: 6 figures (18 images) from Rauch et al., 2003 [MGC:65746]
  6 figures (7 images) from Thisse et al., 2004 [MGC:76834]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa34104 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH bdnf HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH bdnf VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process presynapse assembly (more)
    Cellular Component cytoplasmic vesicle (more)
    Molecular Function growth factor activity (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002072 (1)
  • InterPro:IPR019846 (1)
  • InterPro:IPR020408 (1)
  • InterPro:IPR020430 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00248 (1)
  • Pfam:PF00243 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA bdnf-201 (1) 1866
    bdnf-202 (1) 1100
    bdnf-203 (1) 1446
    bdnf-204 (1) 857
    bdnf-205 (1) 869
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM bdnf No data available
    MARKER RELATIONSHIPS
    bdnfContained in: [BAC] CH73-387L4 (1) (order this), CH211-214A19 (1) (order this), CH211-251J8 (1) (order this)
    bdnfEncodes: [cDNA] MGC:65746 (1) (order this), MGC:76834 (1) (order this), MGC:76835 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131595 (1) 1904bp
    Genomic GenBank:AL935207 (1) 146351bp
    Select Tool
    Polypeptide UniProtKB:Q6NZ01 (1) 270aa
    Sequence Clusters UniGene:132862 (1)
    Sequence Information (all 34)
    OTHER bdnf GENE PAGES
  • Alliance (1)
  • Gene:58118 (1)
  • VEGA:OTTDARG00000011618 (1)
  • Ensembl(GRCz11):ENSDARG00000018817 (2)
  • ORTHOLOGY for bdnf (Chr: 7)
    CITATIONS (99)