Gene

dazl

ID
ZDB-GENE-000405-6
Name
deleted in azoospermia-like
Symbol
dazl Nomenclature History
Previous Names
  • zDAZL
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Exhibits mRNA 3'-UTR binding activity; sequence-specific DNA binding activity; and translation activator activity. Involved in 3'-UTR-mediated mRNA stabilization and negative regulation of gene silencing by miRNA. Localizes to cytoplasm. Is expressed in blastodisc; gonad; unfertilized egg; and yolk. Orthologous to several human genes including DAZL (deleted in azoospermia like).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
34 figures from 25 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dazl Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Spermatogenic failure, susceptibility to}
Associated With dazl Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR037551 DAZ, RNA recognition motif, vertebrates
Domain IPR043628 DAZ domain
Family IPR034779 Deleted in azoospermia-like
Family IPR037366 BOULE/DAZ family
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Domain Details Per Protein
Protein Length BOULE/DAZ family DAZ domain DAZ, RNA recognition motif, vertebrates Deleted in azoospermia-like Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain
UniProtKB:I3IT75 195
UniProtKB:I3ISI8 194
UniProtKB:Q9YGW7 229
UniProtKB:I3ITB8 150
UniProtKB:Q1LUN6 229
UniProtKB:Q1LUN5 212
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations