Gene

actb2

ID
ZDB-GENE-000329-3
Name
actin, beta 2
Symbol
actb2 Nomenclature History
Previous Names
  • bact2
  • bactin2 (1)
  • fa56g06
  • fb38a10
  • wu:fa56g06 (1)
  • wu:fb38a10 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to be a structural constituent of postsynaptic actin cytoskeleton. Predicted to be involved in synaptic vesicle endocytosis. Predicted to localize to several cellular components, including actin filament; dense body; and focal adhesion. Human ortholog(s) of this gene implicated in Baraitser-Winter syndrome and autosomal dominant nonsyndromic deafness 20. Is expressed in several structures, including blastomere; brain; eye; musculature system; and pleuroperitoneal region. Orthologous to several human genes including ACTB (actin beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
22 figures from 17 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With actb2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Baraitser-Winter syndrome Alliance Baraitser-Winter syndrome 1 243310
?Dystonia, juvenile-onset 607371
Associated With actb2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR004001 Actin, conserved site
Conserved_site IPR020902 Actin/actin-like conserved site
Family IPR004000 Actin family
Homologous_superfamily IPR043129 ATPase, nucleotide binding domain
Domain Details Per Protein
Protein Length Actin/actin-like conserved site Actin, conserved site Actin family ATPase, nucleotide binding domain
UniProtKB:A0FKD7 30
UniProtKB:B2GTB1 375
UniProtKB:F1QC15 128
UniProtKB:A8WG05 375
UniProtKB:Q7ZVF9 375
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations