ZFIN ID: ZDB-GENE-000322-2
Gene Name: troponin C type 2 (fast)
Gene Symbol: tnnc2    Nomenclature History

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Previous Names: tnnc, fsTnC (1), wu:fb39a12 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity; calcium ion binding activity; and calcium-dependent protein binding activity. Involved in response to activity. Predicted to localize to the troponin complex. Is expressed in fast muscle cell; heart tube; skeletal muscle; and skeletal muscle cell. Orthologous to human TNNC2 (troponin C2, fast skeletal type).
Genome Resources: Alliance (1),  Gene:58082 (1),  Ensembl(GRCz11):ENSDARG00000070835 (1)
GENE EXPRESSION
All Expression Data: 5 figures from 4 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-tnnc2 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH tnnc2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH tnnc2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process response to activity (more)
Cellular Component troponin complex (more)
Molecular Function calcium ion binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Domain IPR002048 EF-hand domain
Homologous_superfamily IPR011992 EF-hand domain pair
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA tnnc2-201 (1)    Ensembl 1483
tnnc2-202 (1)    Ensembl 954
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM tnnc2 No data available
MARKER RELATIONSHIPS
tnnc2 Contained in: [BAC] RP71-17I16 (1)
tnnc2 Encodes: [EST] fb39a12 (1)
[cDNA] MGC:77594 (1), MGC:174448 (1), MGC:174557 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131563 (1) 1491 nt
Genomic GenBank:CR749762 (1) 174955 nt
Select Tool
Polypeptide UniProtKB:Q9I8U8 (1) 160 aa
Sequence Information (all 20)
ORTHOLOGY for tnnc2 ( Chr: 23 )
CITATIONS (33)