Gene

nme2b.1

ID
ZDB-GENE-000210-32
Name
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
Symbol
nme2b.1 Nomenclature History
Previous Names
  • NDPK-Z1
  • ndpkz1
  • NM23-B
  • NM23-Z1 (1)
  • nm23b
  • nme1 (1)
  • nme2
  • nme2b1 (1)
  • nucleoside diphosphate kinase-Z1
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Exhibits nucleoside diphosphate kinase activity. Involved in GTP biosynthetic process and regulation of angiogenesis. Is expressed in several structures, including digestive system; female organism; gonad; heart; and male organism. Human ortholog(s) of this gene implicated in neuroblastoma; ovary epithelial cancer; and teratoma. Orthologous to several human genes including NME1 (NME/NM23 nucleoside diphosphate kinase 1) and NME1-NME2 (NME1-NME2 readthrough).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nme2b.1 Human Ortholog
No data available
Associated With nme2b.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR023005 Nucleoside diphosphate kinase, active site
Domain IPR034907 Nucleoside diphosphate kinase-like domain
Family IPR001564 Nucleoside diphosphate kinase
Homologous_superfamily IPR036850 Nucleoside diphosphate kinase-like domain superfamily
Domain Details Per Protein
Protein Length Nucleoside diphosphate kinase Nucleoside diphosphate kinase, active site Nucleoside diphosphate kinase-like domain Nucleoside diphosphate kinase-like domain superfamily
UniProtKB:A0A0N4STV7
UniProtKB:A0A0N4STW1 164
UniProtKB:Q7SXG5 153
UniProtKB:Q9PTF5 153
UniProtKB:F1RBS6 153
UniProtKB:Q9IAD3 153
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-nme2 polyclonal IgG Goat
  • WB
Santa Cruz Biotechnology, Inc.
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations