ZFIN ID: ZDB-GENE-000209-4
Gene Name: roundabout, axon guidance receptor, homolog 3 (Drosophila)
Gene Symbol: robo3

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Previous Names: cb503 (1), twi, twitch twice (1)

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 29 figures from 14 publications
Directly Submitted Expression Data: 6 figures (24 images) from Thisse et al., 2001 [cb503]
  6 figures (31 images) from Thisse et al., 2008 [cssl:d102]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Larval:Day 6 (144.0h-168.0h)
  basal plate midbrain region, brain, central nervous system, cerebellum (all 44) expand
Curated Microarray Expression: GEO (1)
PHENOTYPE
Data: 11 figures from 5 publications
Observed in: axon midline choice point recognition, commissural neuron axon guidance, diencephalic nucleus axon, equilibrioception (all 17) expand
DISEASE ASSOCIATED WITH robo3 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Gaze palsy, horizontal, with progressive scoliosis 607313
Ontology GO Term
Biological Process axon guidance (more)
Cellular Component integral component of plasma membrane (more)
Molecular Function protein binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003598 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR003961 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR013098 (1)
  • InterPro:IPR013106 (1)
  • InterPro:IPR013783 (1)
  • PROSITE:PS50835 (1)
  • PROSITE:PS50853 (1)
  • Pfam:PF00041 (1)
  • Pfam:PF07679 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA robo3-001 (1) 5344
    robo3-002 (1) 5056
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM robo3
    Tg(hsp70l:robo3-001,EGFP), Tg(hsp70l:robo3-002,EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    robo3Contained in: [BAC] DKEY-30J19 (1) (order this), DKEY-77G18 (1) (order this), DKEY-119J14 (1) (order this)
    robo3Encodes: [EST] cb503 (1) (order this), fb78e10
    [cDNA] cssl:d102 (1) (order this), MGC:194799 (1) (order this), MGC:194810 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001328416 (1) 5398bp
    Genomic GenBank:AL845320 (1) 183417bp
    Select Tool
    Polypeptide UniProtKB:F1QFK4 (1) 1419aa
    Sequence Clusters UniGene:77473 (1)
    Sequence Information (all 43)
    OTHER robo3 GENE PAGES
  • Gene:30770 (1)
  • VEGA:OTTDARG00000008424 (1)
  • Ensembl(GRCz10):ENSDARG00000005645 (1)
  • ORTHOLOGY for robo3 (Chr: 10)
    CITATIONS (46)