Gene

robo1

ID
ZDB-GENE-000209-3
Name
roundabout, axon guidance receptor, homolog 1 (Drosophila)
Symbol
robo1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have axon guidance receptor activity. Involved in axon guidance and endocardial progenitor cell migration to the midline involved in heart field formation. Predicted to localize to integral component of membrane. Is expressed in basal plate midbrain region; epidermis; nervous system; pectoral fin; and pharyngeal arch. Orthologous to human ROBO1 (roundabout guidance receptor 1).
Genome Resources
Note
None
Expression
All Expression Data
17 figures from 12 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With robo1 Human Ortholog
No data available
Associated With robo1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR003961 Fibronectin type III
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Domain IPR013106 Immunoglobulin V-set domain
Family IPR032986 Roundabout homologue 1
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Fibronectin type III Fibronectin type III superfamily Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin subtype 2 Immunoglobulin V-set domain Roundabout homologue 1
UniProtKB:Q90Z71 376
UniProtKB:A2CEN2 60
UniProtKB:Q98SW4 1675
UniProtKB:F1R2D2 1687
UniProtKB:A2CEN3 31
UniProtKB:A4JYD2 921
UniProtKB:B3DJN8 1649
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-robo1 monoclonal Mouse
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations