ZFIN ID: ZDB-GENE-000208-25
Gene Name: bone morphogenetic protein 7a
Gene Symbol: bmp7a    Nomenclature History

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Previous Names: bmp7 (1), fb83f09, snailhouse, snh, wu:fb83f09 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Exhibits identical protein binding activity and protein heterodimerization activity. Involved in several processes, including determination of bilateral symmetry; negative regulation of endodermal cell fate specification; and post-anal tail morphogenesis. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in prostate cancer. Is expressed in several structures, including epiphysis; gastrula cell; margin; prechordal plate; and tail bud. Orthologous to human BMP7 (bone morphogenetic protein 7).
Genome Resources: Alliance (1),  Gene:30584 (1),  Ensembl(GRCz11):ENSDARG00000018260 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012084Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • p11 Deficiency Unknown Unknown G_RAYS
    p15 Deficiency Unknown Unknown G_RAYS
    sa1343 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15764 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sb1aub Point Mutation Unknown Unknown SPONTANEOUS
  • Zebrafish International Resource Center (ZIRC) (order this)
  • st1 Translocation Unknown Unknown ENU
    ty68a Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-bmp7a
    1
    CRISPR2-bmp7a
    1
    CRISPR3-bmp7a
    1
    MO1-bmp7a N/A 7
    MO2-bmp7a N/A 6
    DISEASE ASSOCIATED WITH bmp7a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH bmp7a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process determination of ventral identity (more)
    Cellular Component extracellular region (more)
    Molecular Function identical protein binding (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA bmp7a-201 (1)    Ensembl 3384
    bmp7a-202 (1)    Ensembl 973
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM bmp7a No data available
    MARKER RELATIONSHIPS
    bmp7a Contained in: [BAC] CH211-253B8 (1)
    [Fosmid] CH1073-430F17 (1)
    bmp7a Encodes: [EST] fb83f09 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131321 (1) 1861 nt
    Genomic GenBank:CR925817 (1) 156864 nt
    Select Tool
    Polypeptide UniProtKB:Q9PTF9 (1) 432 aa
    Sequence Information (all 15)
    ORTHOLOGY for bmp7a ( Chr: 11 )
    CITATIONS (133)