Gene
bmp7a
- ID
- ZDB-GENE-000208-25
- Name
- bone morphogenetic protein 7a
- Symbol
- bmp7a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Enables identical protein binding activity and protein heterodimerization activity. Acts upstream of or within several processes, including BMP signaling pathway; determination of bilateral symmetry; and negative regulation of endodermal cell fate specification. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including forebrain; gastrula cell; margin; prechordal plate; and tail bud. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human BMP7 (bone morphogenetic protein 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 27 figures from 23 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 24 figures from 16 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017948 | Transforming growth factor beta, conserved site |
| Domain | IPR001111 | TGF-beta, propeptide |
| Domain | IPR001839 | Transforming growth factor-beta, C-terminal |
| Family | IPR015615 | Transforming growth factor-beta-related |
| Homologous_superfamily | IPR029034 | Cystine-knot cytokine |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cystine-knot cytokine | TGF-beta, propeptide | Transforming growth factor beta, conserved site | Transforming growth factor-beta, C-terminal | Transforming growth factor-beta-related |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q9PTF9 | InterPro | 432 |
Interactions and Pathways
No data available
Plasmids