Gene

anos1a

ID
ZDB-GENE-000201-9
Name
anosmin 1a
Symbol
anos1a Nomenclature History
Previous Names
  • anosmin-1a (1)
  • kal1a
  • kal1.1
  • wu:fl91z45
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Is predicted to enable peptidase inhibitor activity. Involved in neuron differentiation. Acts upstream of or within neuron differentiation; olfactory bulb development; and posterior lateral line development. Predicted to be located in extracellular region. Is expressed in several structures, including digestive system; nervous system; neural tube; otic vesicle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 1 with or without anosmia. Orthologous to human ANOS1 (anosmin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
28 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With anos1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypogonadotropic hypogonadism 1 with or without anosmia Alliance Hypogonadotropic hypogonadism 1 with or without anosmia (Kallmann syndrome 1) 308700
Associated With anos1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003961 Fibronectin type III
Domain IPR008197 WAP-type 'four-disulfide core' domain
Domain IPR040957 Anosmin-1, cysteine rich domain
Family IPR042447 Anosmin-1
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Homologous_superfamily IPR036645 Elafin-like superfamily
Domain Details Per Protein
Protein Length Anosmin-1 Anosmin-1, cysteine rich domain Elafin-like superfamily Fibronectin type III Fibronectin type III superfamily Immunoglobulin-like fold WAP-type 'four-disulfide core' domain
UniProtKB:F1R469 652
UniProtKB:Q6P938 652
UniProtKB:A0A0B5JS68 652
UniProtKB:Q9IAR4 652
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-anos1a polyclonal Rabbit
  • IHC
  • WB
3
Ab2-anos1a polyclonal Rabbit
  • IHC
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations