ZFIN ID: ZDB-FISH-150901-5555
Fish name: WT + MO1-npc1
Genotype: WT
Targeting Reagent: MO1-npc1

HUMAN DISEASE MODELED by WT + MO1-npc1
No data available
GENE EXPRESSION
Gene expression in WT + MO1-npc1
Expressed Gene Structure Conditions Figures
foxd3 whole organism anterior region standard conditions Fig. 9 from Schwend et al., 2011
pcdh8 segmental plate standard conditions Fig. 9 from Schwend et al., 2011
ta forerunner cell group, mesoderm, notochord (all 4) expand standard conditions Fig. 4Fig. 9 from Schwend et al., 2011
PHENOTYPE 
Phenotype in WT + MO1-npc1
Phenotype Conditions Figures
actin cytoskeleton organization disrupted, abnormal standard conditions Fig. 7 from Schwend et al., 2011
brain morphology, abnormal standard conditions Fig. 4 from Louwette et al., 2013
cell death increased occurrence, abnormal standard conditions Fig. 9 from Schwend et al., 2011
epiboly involved in gastrulation with mouth forming second delayed, abnormal standard conditions Fig. 3Fig. 4Fig. 6 from Schwend et al., 2011
eye morphology, abnormal standard conditions Fig. 4 from Louwette et al., 2013
head malformed, abnormal standard conditions Fig. 4 from Louwette et al., 2013
intracellular cholesterol transport disrupted, abnormal standard conditions Fig. 7 with image from Chu et al., 2015
lateral mesoderm increased width, abnormal standard conditions Fig. 9 from Schwend et al., 2011
notochord increased width, abnormal standard conditions Fig. 9 from Schwend et al., 2011
programmed cell death increased occurrence, abnormal standard conditions Fig. 4 from Louwette et al., 2013
regulation of cholesterol storage disrupted, abnormal standard conditions Fig. 4 from Louwette et al., 2013
segmental plate increased width, abnormal standard conditions Fig. 9 from Schwend et al., 2011
whole organism decreased length, abnormal standard conditions Fig. 9 from Schwend et al., 2011
whole organism viability, abnormal standard conditions text only from Schwend et al., 2011
whole organism cholesterol increased amount, abnormal standard conditions Fig. 7 with image from Chu et al., 2015

CITATIONS  (4)