ZFIN ID: ZDB-FISH-150901-26472
Fish name: WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3
Genotype: WT
Targeting Reagent: MO3-sox2, MO4-sox2, MO3-sox3, MO4-sox3, MO1-sox19a, MO2-sox19a, MO1-sox19b, MO2-sox19b
HUMAN DISEASE MODELED by WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3
No data available
GENE EXPRESSION
Gene expression in WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3
RNA expression
Expressed Gene Structure Conditions Figures
ascl1a standard conditions Fig. 5 with image from Okuda et al., 2010
bmp2b standard conditions Fig. 4 with image from Okuda et al., 2010
bmp4 standard conditions Fig. 4 with image from Okuda et al., 2010
bmp7a standard conditions Fig. 4 with image from Okuda et al., 2010
cdh1 standard conditions Fig. 4 with image from Okuda et al., 2010
chrd standard conditions Fig. 4 with image from Okuda et al., 2010
ctslb standard conditions Fig. 2 with image from Okuda et al., 2010
cyp26a1 standard conditions Fig. 5 with image from Okuda et al., 2010
dlx3b standard conditions Fig. 2 with imageFig. 3 with image from Okuda et al., 2010
egr2b standard conditions Fig. 3 with image from Okuda et al., 2010
en2a standard conditions Fig. 3 with image from Okuda et al., 2010
eve1 standard conditions Fig. 4 with image from Okuda et al., 2010
foxd3 standard conditions Fig. 5 with image from Okuda et al., 2010
foxi1 standard conditions Fig. 3 with image from Okuda et al., 2010
gata2a standard conditions Fig. 4 with image from Okuda et al., 2010
gbx1 standard conditions Fig. 3 with image from Okuda et al., 2010
gsc standard conditions Fig. 4 with image from Okuda et al., 2010
her3 standard conditions Fig. 5 with image from Okuda et al., 2010
hesx1 standard conditions Fig. 2 with imageFig. 3 with imageFig. 5 with image from Okuda et al., 2010
hoxb1a standard conditions Fig. 5 with image from Okuda et al., 2010
hoxb1b standard conditions Fig. 2 with imageFig. 3 with image from Okuda et al., 2010
klf2a standard conditions Fig. 2Fig. S8 from Leichsenring et al., 2013
krt5 standard conditions Fig. S8 from Leichsenring et al., 2013
krt17 standard conditions Fig. S8 from Leichsenring et al., 2013
mafba standard conditions Fig. 5 with image from Okuda et al., 2010
mdkb standard conditions Fig. 5 with image from Okuda et al., 2010
myod1 standard conditions Fig. 3 with image from Okuda et al., 2010
neurog1 standard conditions Fig. 2 with imageFig. 5 with image from Okuda et al., 2010
nkx1.2la standard conditions Fig. 3 with image from Okuda et al., 2010
nog1 standard conditions Fig. 4 with image from Okuda et al., 2010
otx2b standard conditions Fig. 3 with image from Okuda et al., 2010
pax2a standard conditions Fig. 2 with image from Okuda et al., 2010
pcdh18a standard conditions Fig. 4 with image from Okuda et al., 2010
pcdh18b standard conditions Fig. 4 with image from Okuda et al., 2010
rest standard conditions Fig. 5 with image from Okuda et al., 2010
rx3 standard conditions Fig. 3 with imageFig. 5 with image from Okuda et al., 2010
shha standard conditions Fig. 5 with image from Okuda et al., 2010
shhb standard conditions Fig. 5 with image from Okuda et al., 2010
sox2 standard conditions Fig. 3 with image from Okuda et al., 2010
sox3 standard conditions Fig. 3 with image from Okuda et al., 2010
sox19a standard conditions Fig. 3 with image from Okuda et al., 2010
sox19b standard conditions Fig. 3 with image from Okuda et al., 2010
stmn2a standard conditions Fig. 5 with image from Okuda et al., 2010
szl standard conditions Fig. 4 with image from Okuda et al., 2010
tbxta standard conditions Fig. 2 with imageFig. 3 with image from Okuda et al., 2010
tuba1b standard conditions Fig. 5 with image from Okuda et al., 2010
wnt4 standard conditions Fig. 4 with image from Okuda et al., 2010
wnt5b standard conditions Fig. 4 with image from Okuda et al., 2010
wnt11 standard conditions Fig. 4 with image from Okuda et al., 2010
wnt11r standard conditions Fig. 4 with image from Okuda et al., 2010
zic1 standard conditions Fig. 3 with imageFig. 5 with image from Okuda et al., 2010
zic2b standard conditions Fig. 3 with image from Okuda et al., 2010
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3
Phenotype Conditions Figures
anterior neural plate formation disrupted, abnormal standard conditions Fig. 5 with image from Okuda et al., 2010
axis shortened, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Okuda et al., 2010
brain development disrupted, abnormal standard conditions Fig. 5 with image from Okuda et al., 2010
central nervous system abnormal, abnormal standard conditions Fig. 1 with image from Okuda et al., 2010
central nervous system development disrupted, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Okuda et al., 2010
convergent extension disrupted, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Okuda et al., 2010
epiboly delayed, abnormal standard conditions Fig. 2Fig. S8 from Leichsenring et al., 2013
Fig. 1 with image from Okuda et al., 2010
head aplastic, abnormal standard conditions Fig. 2Fig. S8 from Leichsenring et al., 2013
hindbrain development disrupted, abnormal standard conditions Fig. 5 with image from Okuda et al., 2010
mesoderm increased width, abnormal standard conditions Fig. 3 with image from Okuda et al., 2010
neural plate increased width, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Okuda et al., 2010
neural plate development disrupted, abnormal standard conditions Fig. 3 with image from Okuda et al., 2010
neurogenesis disrupted, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Okuda et al., 2010
notochord broad, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Okuda et al., 2010
prechordal plate increased distance notochord, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Okuda et al., 2010
somite malformed, abnormal standard conditions Fig. 2Fig. S8 from Leichsenring et al., 2013
tail bud aplastic, abnormal standard conditions Fig. 2Fig. S8 from Leichsenring et al., 2013
whole organism truncated, abnormal standard conditions Fig. 2Fig. S8 from Leichsenring et al., 2013
whole organism wholly dorsalized, abnormal standard conditions Fig. 4 with image from Okuda et al., 2010

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