ZFIN ID: ZDB-FISH-150901-12789
Fish name: WT + MO4-tp53
Genotype: WT
Targeting Reagent: MO4-tp53

HUMAN DISEASE MODELED by WT + MO4-tp53
No data available
GENE EXPRESSION
Gene expression in WT + MO4-tp53
Expressed Gene Structure Conditions Figures
alcama atrioventricular canal endocardium standard conditions Fig. 4 with image from Smith et al., 2011
axin2 intestinal epithelium standard conditions Fig. 9 with image from Mahmoudi et al., 2010
baxa (not) whole organism standard conditions Fig. S3 with image from Chakraborty et al., 2009
bbc3 whole organism standard conditions Fig. 6 from Rodríguez-Aznar et al., 2011
casp8 whole organism standard conditions Fig. 4 with image from Espín et al., 2013
cdkn1a (not) whole organism standard conditions Fig. 3 with image from Provost et al., 2012
Fig. S3 with image from Chakraborty et al., 2009
col2a1a floor plate, hypochord, notochord (all 4) expand control Fig. 4 with image from Moreno-Ayala et al., 2015
Fig. 6 from van Boxtel et al., 2011
crestin pharyngeal arch 3-7 neural crest cell standard conditions Fig. 8 with image from Xia et al., 2013
cyp26a1 trunk anterior region standard conditions Fig. 7 with image from Feng et al., 2010
dlx2a diencephalon, dorsal telencephalon, neural crest (all 4) expand standard conditions Fig. 6 from van Boxtel et al., 2011
Fig. 4 with image from Viktorin et al., 2009
dmbx1a eye standard conditions Fig. 2 from Liu et al., 2008
elavl3 diencephalon, telencephalon standard conditions Fig. 4 with image from Viktorin et al., 2009
elavl4 diencephalon, dorsal telencephalon standard conditions Fig. 4 with image from Viktorin et al., 2009
emx1 dorsal telencephalon standard conditions Fig. 4 with image from Viktorin et al., 2009
emx3 telencephalon standard conditions Fig. 5 with image from Viktorin et al., 2009
eomesa dorsal telencephalon standard conditions Fig. 3 with imageFig. 4 with image from Viktorin et al., 2009
fabp2 intestine standard conditions Fig. 8 with image from Mahmoudi et al., 2010
fezf2 diencephalon, dorsal telencephalon standard conditions Fig. 4 with image from Viktorin et al., 2009
fgf8a diencephalon, telencephalon, ventral telencephalon standard conditions Fig. 4 with image from Viktorin et al., 2009
foxg1a telencephalon, ventral telencephalon standard conditions Fig. 4 with imageFig. 5 with image from Viktorin et al., 2009
fzd8a diencephalon, ventral telencephalon standard conditions Fig. 4 with image from Viktorin et al., 2009
gsc pharyngeal arch 2 mesenchyme condensation cell standard conditions Fig. 6 from van Boxtel et al., 2011
hand2 pharyngeal arch cranial neural crest cell standard conditions Fig. 6 from van Boxtel et al., 2011
has2 atrioventricular canal endocardium standard conditions Fig. 4 with image from Smith et al., 2011
lhx5 diencephalon, dorsal telencephalon standard conditions Fig. 4 with image from Viktorin et al., 2009
mbpa hindbrain oligodendrocyte control Fig. 4 from Mathews et al., 2016
hindbrain oligodendrocyte chemical treatment by environment: sirolimus Fig. 4 from Mathews et al., 2016
mdm2 (not) whole organism standard conditions Fig. S3 with image from Chakraborty et al., 2009
mpx intermediate cell mass of mesoderm neutrophil standard conditions Fig. 3 with image from Provost et al., 2012
neurod1 diencephalon, dorsal telencephalon standard conditions Fig. 4 with image from Viktorin et al., 2009
neurod6b dorsal telencephalon standard conditions Fig. 4 with image from Viktorin et al., 2009
otx2 midbrain hindbrain boundary standard conditions Fig. S3 with image from Schaffer et al., 2014
pax6a diencephalon, dorsal telencephalon, eye (all 4) expand standard conditions Fig. 4 with image from Viktorin et al., 2009
Fig. 2 from Liu et al., 2008
plp1a hindbrain oligodendrocyte control Fig. 4 from Mathews et al., 2016
hindbrain oligodendrocyte chemical treatment by environment: U0126 Fig. 4 from Mathews et al., 2016
prl prolactin secreting cell standard conditions Fig. 8 from Graf et al., 2015
ptch1 trunk standard conditions Fig. S5 with image from Corallo et al., 2013
reln diencephalon standard conditions Fig. 4 with image from Viktorin et al., 2009
shha floor plate control Fig. 4 with image from Moreno-Ayala et al., 2015
slc17a6a diencephalon, dorsal telencephalon standard conditions Fig. 4 with image from Viktorin et al., 2009
slc17a6b diencephalon, dorsal telencephalon standard conditions Fig. 4 with image from Viktorin et al., 2009
sox9a pharyngeal arch chondrocyte standard conditions Fig. 6 from van Boxtel et al., 2011
sox10 cranial neural crest standard conditions Fig. 6 from van Boxtel et al., 2011
ta notochord control Fig. 4 with image from Moreno-Ayala et al., 2015
tcf4 dorsal telencephalon standard conditions Fig. 4 with image from Viktorin et al., 2009
tp53 (not) gut chemical treatment: seliciclib Fig. 4 from Lee et al., 2008
(not) gut, (not) whole organism standard conditions Fig. 3 with image from Provost et al., 2012
Fig. S3 with image from Chakraborty et al., 2009
Fig. 3Fig. 4 from Lee et al., 2008
wnt7ba diencephalon, telencephalon diencephalon boundary standard conditions Fig. 4 with image from Viktorin et al., 2009
wnt7bb diencephalon, telencephalon diencephalon boundary standard conditions Fig. 4 with image from Viktorin et al., 2009
PHENOTYPE 
Phenotype in WT + MO4-tp53
Phenotype Conditions Figures
adenohypophysis has normal numbers of parts of type prolactin secreting cell, normal standard conditions Fig. 8 from Graf et al., 2015
apoptotic process decreased occurrence, abnormal standard conditions Fig. S3 with image from Chakraborty et al., 2009
Fig. S4 from Zeng et al., 2007
apoptotic process disrupted, abnormal radiation Fig. S6 with image from Sidi et al., 2008
apoptotic process occurrence, normal standard conditions Fig. 6 with image from Paridaen et al., 2011
apoptotic process rate, normal x-ray Fig. 1 from Davidson et al., 2008
apoptotic process rate, normal standard conditions Fig. 1 from Davidson et al., 2008
blood cell normal amount, normal standard conditions Fig. 5 with image from Imamura et al., 2008
brain morphology, normal standard conditions Fig. 5 with image from Azuma et al., 2007
caudal vein plexus structure, normal standard conditions Fig. 5 with image from Imamura et al., 2008
cerebellum apoptotic process occurrence, normal control Fig. 6 with image from Hu et al., 2015
ciliary marginal zone apoptotic process occurrence, normal control Fig. 6 with image from Hu et al., 2015
convergent extension involved in axis elongation occurrence, normal standard conditions Fig. 5 from Zoeller et al., 2009
double-strand break repair via homologous recombination increased frequency, abnormal standard conditions Fig. 1 from Gong et al., 2015
double-strand break repair via nonhomologous end joining increased frequency, abnormal standard conditions Fig. 1 from Gong et al., 2015
double-strand break repair via single-strand annealing increased frequency, abnormal standard conditions Fig. 1 from Gong et al., 2015
head morphology, normal standard conditions Fig. 3 from Davidson et al., 2008
intermediate cell mass of mesoderm neutrophil present, normal standard conditions Fig. 3 with image from Provost et al., 2012
intestine well differentiated, abnormal standard conditions Fig. 8 with image from Mahmoudi et al., 2010
nervous system structure, normal standard conditions Fig. 2 with image from Robu et al., 2007
neuron apoptotic process process quality, normal standard conditions Fig. 1 from Ko et al., 2011
neuron differentiation occurrence, normal standard conditions Fig. 2 from Rodríguez-Aznar et al., 2013
notochord morphology, normal standard conditions Fig. S1 with image from Corallo et al., 2013
nucleate erythrocyte immature, abnormal standard conditions Fig. 5 with image from Imamura et al., 2008
optic tectum apoptotic process occurrence, normal control Fig. 6 with image from Hu et al., 2015
renal system process occurrence, normal standard conditions Fig. 5 from Davidson et al., 2008
response to X-ray disrupted, abnormal x-ray Fig. 1 from Davidson et al., 2008
retinal ganglion cell layer maturity, normal standard conditions Fig. 6 with image from Paridaen et al., 2011
serotonin metabolic process process quality, normal standard conditions Fig. 3 from Ren et al., 2013
spinal cord has normal numbers of parts of type neuron, normal standard conditions Fig. 2 from Rodríguez-Aznar et al., 2013
tail bud structure, normal ultraviolet light Fig. 5 with image from Mei et al., 2008
whole organism decreased sensitivity to irradiation, abnormal radiation Fig. S6 with image from Sidi et al., 2008
whole organism morphology, normal standard conditions Fig. 3 with image from Luo et al., 2013
Fig. 7 from Yue et al., 2013
Fig. 3 with image from Provost et al., 2012
Fig. S6 from Chopra et al., 2010
Fig. 2 from Wood et al., 2009
Fig. 5 from Zoeller et al., 2009
Fig. 3 with image from Mei et al., 2008
Fig. S2 from Zoeller et al., 2008
Fig. 1 with image from Robu et al., 2007
whole organism semi-viable, abnormal x-ray Fig. 1 from Davidson et al., 2008
whole organism viable, normal standard conditions Fig. 1 from Davidson et al., 2008

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