FIGURE

Fig. 6

ID

ZDB-FIG-240402-11

Publication

Liang et al., 2024 - A novel gene-trap line reveals the dynamic patterns and essential roles of cysteine and glycine-rich protein 3 in zebrafish heart development and regeneration

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Fig. 6

Csrp3 deficiency impairs injury-induced CM dedifferentiation and sarcomere reassembly. A Immunostaining of cTnT indicated that sarcomere disassembly of 218A CMs was not blocked but instead exacerbated during regeneration while sarcomere reassembly was hindered. Scale bars, 20 μm. B WISH showed reduced expression of cardiogenic factors nkx2.5 and hand2 in ablated 218A larval hearts during regeneration. Scale bars, 50 μm. C Immunostaining showed reduced embryonic Myh7 signal in the border zone of injured 218A adult ventricle at 7 dpci. Scale bars, 100 μm

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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