FIGURE

Fig. 3.

ID

ZDB-FIG-231018-29

Publication

Ali et al., 2023 - Loss of a cilia-associated gene, pkd1l1, causes biliary defects in zebrafish: Implications for Biliary Atresia Splenic Malformation

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Fig. 3.

pkd1l1 knockout alters hepatobiliary function. (A) Representative images of PED6 uptake in larvae showing typical normal (top), faint (middle) and absent (bottom) fluorescence (red circles) in gallbladders. Scale bars: 500 µm. (B) Quantification of PED6 uptake showed an increase number of absent gallbladders in pkd1l1 mutant (n=145) compared to wild-type (n=84) larvae (***P<0.001; χ² test), reflecting defects in biliary function.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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