FIGURE
Fig. 3
- ID
- ZDB-FIG-230403-58
- Publication
- Begeman et al., 2022 - Regeneration and developmental enhancers are differentially compatible with minimal promoters
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Fig. 3
Regeneration enhancer activity in hearts is preferentially compatible with P0.8 and P2. (A) Experimental design. Transgenic constructs were injected into one-cell-stage Tg(cmlc2:mCherry-NTR) embryos, larvae were treated with Mtz for 24 h starting at 3 dpf to ablate cardiomyocytes, and EGFP expression was observed at 6 dpf. (B) 6-dpf F0 regenerating hearts following Mtz-induced cardiomyocyte ablation. Arrows indicate EGFP expression. (C) Table of larvae displaying cardiac EGFP expression for each promoter alone or when paired with LEN or 103runx1EN. Scale bar: 50 μm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 492, Begeman, I.J., Emery, B., Kurth, A., Kang, J., Regeneration and developmental enhancers are differentially compatible with minimal promoters, 47-58, Copyright (2022) with permission from Elsevier. Full text @ Dev. Biol.