FIGURE

Figure 1

ID

ZDB-FIG-211029-135

Publication

Lam et al., 2021 - Systems Analysis Reveals Ageing-Related Perturbations in Retinoids and Sex Hormones in Alzheimer's and Parkinson's Diseases

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Figure 1

Overview and exploratory data analysis. (A) Workflow for the analysis of human AD and PD samples. (B) AD and PD samples were clustered into k clusters without supervision on the basis of normalised expression counts. Results are shown for k = 3 and 1000 bootstrap replicates. Colour bars indicate cluster identity for each sample. For 2 ≤ k ≤ 7, refer to Figure S1. (C) Normalised expression data from AD, PD, and control samples were projected onto 2-D space using t-distributed stochastic neighbour embedding (t-SNE). Points are coloured according to cluster assignment by unsupervised clustering. For further data visualisation, refer to Figure S2.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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