FIGURE

FIGURE 5

ID
ZDB-FIG-210818-6
Publication
Gao et al., 2021 - Probing Synergistic Targets by Natural Compounds for Hepatocellular Carcinoma
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FIGURE 5

The workflow of systematic processes to identify key synergy-mediated players. Step 1: Choosing the natural compound pair from the natural compounds library. Step 2: Obtaining DEGs from transcriptomics or proteomics profiling. Step 3: Mapping DEGs to cancer signaling transduction networks. Step 4: Inferring key synergy-mediating targets among DEGs based on network topology and empirical experience. Step 5: Validating suspected targets through in vitro and in vivo experiments. Step 6: Conducting survival analysis in clinical samples. Step 7: Choosing the best candidates.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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