FIGURE

Figure 5.

ID

ZDB-FIG-200916-23

Publication

Ichino et al., 2020 - Building the vertebrate codex using the gene breaking protein trap library

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Figure 5.

Disease-associated human orthologs of the GBT trapped genes are implicated in human genetic disorders of multiple organ systems.

(A) Representative human orthologs of the GBT-tagged genes are associated with genetic disorders in multi-organ systems. Image provided by Mayo Clinic Media Services. Underline: Disease causative genes with documentations of established disease model in mouse or zebrafish (B) Area proportional Venn diagram of 64 human orthologs tagged that are associated with human genetic disorders. 40 human orthologs of GBT-tagged genes are associated with human genetic disorders without an established disease model in zebrafish or mouse. Area proportional Venn diagram was produced using BioVenn (http://www.biovenn.nl/).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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