FIGURE
Fig. 1
- ID
- ZDB-FIG-180828-13
- Publication
- Tan et al., 2018 - Human MLL-AF9 Overexpression Induces Aberrant Hematopoietic Expansion in Zebrafish
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Fig. 1
MLL-AF9 overexpression in zebrafish embryos and activation of MLL downstream genes. MLL-AF9 mRNA was injected into zebrafish at the 1–2-cell stage (around 5ng per embryo). Injected embryos and control embryos were harvested at 48hpf. (a) Western blotting of the N-terminus of the MLL protein in MLL-AF9-injected and control embryos. (b) Relative expression of MLL downstream genes analyzed by qRT-PCR. (c–e) WISH assays of hoxa9a, hoxb5a, and meis1 in MLL-AF9-injected and control embryos at 24hpf. (f, g) Morphology of the hematopoietic cells of control embryos and MLL-AF9-injected embryos at 48 hpf. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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