FIGURE

Fig. 4

ID

ZDB-FIG-180628-4

Publication

Kumar et al., 2018 - Microvillar and ciliary defects in zebrafish lacking an actin-binding bioactive peptide amidating enzyme

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Fig. 4

Heteroallelic pam^−/− zebrafish display severe edema. Heterozygous zebrafish bearing different pam^mbg alleles were crossed and the phenotypes of the resulting pam^−/− heteroallelic embryos and their wildtype siblings were examined at 5 dpf. Wildtype pam^+/+ embryos developed normally (A,C). In contrast, heteroallelic pam^−/− homozygotes (pam^mbg5/pam^mbg9 and pam^mbg5/pam^mbg10) derived from pam^mbg5+/− × pam^mbg9+/− and pam^mbg5+/− × pam^mbg10+/− crosses exhibited severe edema (B,D).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pam^mbg9/+; pam^mbg5/+ pam^mbg10/+; pam^mbg5/+
Observed In:	gut heart
Stage:	Day 5

Phenotype Detail

Acknowledgments

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