ZFIN ID: ZDB-FIG-180329-27
Leyk et al., 2017 - HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness. Cell Death & Disease   8:e3028 Full text @ Cell Death Dis.
EXPRESSION / LABELING:
Antibodies:
Fish:
Condition:
Anatomical Term:
Stage: Day 5
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage: Day 5

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-tuba WB WT standard conditions Day 5 eye
WB WT chemical treatment by environment: tubastatin A Day 5 eye
WB atp6v0e1ucd6/ucd6 standard conditions Day 5 eye
WB atp6v0e1ucd6/ucd6 chemical treatment by environment: tubastatin A Day 5 eye
Ab3-tuba WB WT standard conditions Day 5 eye
WB WT chemical treatment by environment: tubastatin A Day 5 eye
WB atp6v0e1ucd6/ucd6 standard conditions Day 5 eye
WB atp6v0e1ucd6/ucd6 chemical treatment by environment: tubastatin A Day 5 eye
Phenotype Details
Fish Conditions Stage Phenotype
atp6v0e1ucd6/ucd6 standard conditions Day 5 ciliary marginal zone apoptotic chromosome condensation increased occurrence, abnormal
Day 5 ciliary marginal zone cell apoptotic, abnormal
Day 5 locomotory behavior process quality, abnormal
Day 5 optokinetic behavior disrupted, abnormal
Day 5 photoreceptor cell morphology, abnormal
atp6v0e1ucd6/ucd6 chemical treatment by environment: tubastatin A Day 5 ciliary marginal zone apoptotic chromosome condensation occurrence, ameliorated
Day 5 ciliary marginal zone apoptotic process occurrence, ameliorated
Day 5 eye ab1-tuba labeling increased amount, abnormal
Day 5 locomotory behavior process quality, ameliorated
Day 5 optokinetic behavior process quality, ameliorated
Day 5 photoreceptor cell morphology, ameliorated
Full text @ Cell Death Dis.