ZFIN ID: ZDB-FIG-180119-14
Hou et al., 2017 - Clinico-biological significance of suppressor of cytokine signaling 1 expression in acute myeloid leukemia. Blood cancer journal   7:e588 Full text @ Blood Cancer J
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Adult

Fig. 4

Histopathological examination of the kidney marrow, spleen and liver of spi1:SOCS1-2A-mCherry or SOCS1/FLT3-ITD double transgenic fish. (a and b) Hematoxylin and eosin stains of the kidney marrow, spleen and liver from 9- and 12-month old spi1:SOCS1-2A-mCherry transgenic, SOCS1/FLT3-ITD double transgenic and wild-type fish. Kidney marrows from spi1:SOCS1-2A-mCherry transgenic or SOCS1/FLT3-ITD double transgenic fish show increased infiltration by myeloid cells compared with wild-type fish.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
twu101Tg; twu103Tg (AB) standard conditions Adult head kidney myeloid cell infiltrative, abnormal
Adult head kidney myeloid leukaemia present, abnormal
Adult head kidney myeloid lineage restricted progenitor cell increased amount, abnormal
Adult head kidney structure, abnormal
Adult liver structure, abnormal
twu103Tg (AB) standard conditions Adult head kidney myeloid cell infiltrative, abnormal
Adult head kidney myeloid leukaemia present, abnormal
Adult head kidney structure, abnormal
Adult spleen structure, abnormal
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Blood Cancer J