FIGURE

Fig. 7

ID

ZDB-FIG-180112-19

Publication

Kim et al., 2017 - High Consumption of Iron Exacerbates Hyperlipidemia, Atherosclerosis, and Female Sterility in Zebrafish via Acceleration of Glycation and Degradation of Serum Lipoproteins

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Fig. 7

Histological analysis of hepatic tissue. (A) Representative sections for histological assessment of hepatic microsections after consumption of ferrous ion (0.05% and 0.1% wt/wt in diet) for 24 weeks under normal diet (ND) or high cholesterol diet (HCD). Extent of fatty liver changes was compared by oil red O staining. Production of reactive oxygen species was determined by Dihydroethidium (DHE) staining and visualized by fluorescence (Ex = 588 nm, Em = 615 nm); (B) Quantification of oil red O stained area and DHE stained area by computer-assisted morphometry using Image Proplus software (version 4.5.1.22; Media Cybernetics, Rockville, MD, USA). *, p < 0.05; **, p < 0.01.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	brs^b2/b2 (AB)
Conditions:	chemical treatment by diet: ferrous ammonium sulfate hexahydrate high cholesterol chemical treatment by diet: ferrous ammonium sulfate hexahydrate, high cholesterol
Observed In:	liver lipid liver reactive oxygen species
Stage:	Adult

Phenotype Detail

Acknowledgments

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