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ZIRC
ZFIN ID: ZDB-FIG-180104-15
Wilk et al., 2017 - The Effect of Retinal Melanin on Optical Coherence Tomography Images. Translational vision science & technology   6:8 Full text @ Transl Vis Sci Technol
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Adult

Fig. 4

Differences in LRP peaks with pigmentation in zebrafish. (A) Wild type fish with consistent RPE reflectance and width. (B) Albino fish, whose RPE is distinctly dimmer than the WT. (C) Mosaic fish, where the left LRP was generated in an area with melanin pigment and the right LRP was generated in an area lacking pigment. When melanin in present, the RPE band is wider and has increased reflectance. When melanin is absent, the sclera also is visible posterior to the RPE and choroid. Wild type and albino images are 225 μm wide. Mosaic fish image is 475 μm wide. All images are 479 μm tall. Images are displayed in linear format with intensity values normalized to stretch between 0 and 255 for display only. RNFL, retinal nerve fiber layer; IPL, inner plexiform layer; OPL, outer plexiform layer; PR, photoreceptor layers.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
slc45a2b4/b4 standard conditions Adult retinal pigmented epithelium reflectivity, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Translational vision science & technology for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Transl Vis Sci Technol