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ZIRC
ZFIN ID: ZDB-FIG-171228-33
Pazhakh et al., 2017 - A GCSFR/CSF3R zebrafish mutant models the persistent basal neutrophil deficiency of severe congenital neutropenia. Scientific Reports   7:44455 Full text @ Sci. Rep.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Knockdown Reagent:
Anatomical Term:
Stage: Adult
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Adult

Fig. 4

Neutrophil deficiency in csf3r null adults.

(a,b) Fluorescent photomicrographs of 5 month old adult Tg(mpx:EGFP) zebrafish tail fins showing reduced numbers of EGFP-positive neutrophils in csf3r null (b) vs WT (a) animals. (c) Quantification of tail fin neutrophil density. nā€‰=ā€‰4ā€“5 animals/genotype as shown.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
GFP i114Tg control Adult neutrophil IFL
i114Tg + CRISPR2-csf3r standard conditions Adult neutrophil IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
i114Tg + CRISPR2-csf3r standard conditions Adult neutrophil GFP expression decreased distribution, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Scientific Reports for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Sci. Rep.