FIGURE

Fig. S2

ID
ZDB-FIG-160317-25
Publication
Sempou et al., 2016 - Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo
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Fig. S2

Fyn and Yes act downstream of PrP-1 during epiboly. A. Immunofluorescence (IF) of E-cadherin and β-catenin in 6 hpf Fyn and Yes single knockdown embryos. Scale bar = 10 µM. B. Photos of live embryos at 6 hpf displaying normal or arrested epiboly. Recovery of epiboly is visible in PrP-1 morphants expressing EGFP-tagged WT or CA Fyn and Yes. Lissamine (Lis)-tagged PrP-1 morpholinos were used.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Mol. Neurodegener.