ZFIN ID: ZDB-FIG-160316-6
Tsai et al., 2016 - Genome-wide screening identifies a KCNIP1 copy number variant as a genetic predictor for atrial fibrillation. Nature communications   7:10190 Full text @ Nat. Commun.
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage Range: Protruding-mouth to Day 5
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Protruding-mouth

Fig. S3

Cardiac expression of KCNIP1 and gross phenotypes of KCNIP1-knockdown, overexpression and control hearts. (a)Whole mount in situ hybridization of 3dpf, 4-dpf and 5dpfembryos shows expression (dark brown staining) of KCNIP1 in the heart(arrows). dpf, days post-fertilization.(b) Bright-field micrographs of anesthetized 3 days post fertilization control embryos (CTL) and embryos injected with KCNIP1 morpholinos (KCNIP1 MO) or mRNA (KCNIP1 OE). Scale bar, 500 ┬Ám.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
kcnip1b TL standard conditions Protruding-mouth heart ISH
Day 4 heart ISH
Day 5 heart ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
TL + MO1-kcnip1b standard conditions Protruding-mouth atrium cardiac muscle cell action potential process quality, abnormal
Protruding-mouth embryo development process quality, normal
Protruding-mouth heart contraction process quality, normal
Acknowledgments:
ZFIN wishes to thank the journal Nature communications for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Nat. Commun.