ZFIN ID: ZDB-FIG-160316-6
Tsai et al., 2016 - Genome-wide screening identifies a KCNIP1 copy number variant as a genetic predictor for atrial fibrillation. Nature communications   7:10190 Full text @ Nat. Commun.
Anatomical Term:
Stage Range: Protruding-mouth to Day 5
Knockdown Reagent:
Observed In:
Stage: Protruding-mouth

Fig. S3

Cardiac expression of KCNIP1 and gross phenotypes of KCNIP1-knockdown, overexpression and control hearts. (a)Whole mount in situ hybridization of 3dpf, 4-dpf and 5dpfembryos shows expression (dark brown staining) of KCNIP1 in the heart(arrows). dpf, days post-fertilization.(b) Bright-field micrographs of anesthetized 3 days post fertilization control embryos (CTL) and embryos injected with KCNIP1 morpholinos (KCNIP1 MO) or mRNA (KCNIP1 OE). Scale bar, 500 ┬Ám.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
kcnip1b TL standard conditions Protruding-mouth heart ISH
Day 4 heart ISH
Day 5 heart ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
TL + MO1-kcnip1b standard conditions Protruding-mouth atrium cardiac muscle cell action potential process quality, abnormal
Protruding-mouth embryo development process quality, normal
Protruding-mouth heart contraction process quality, normal
ZFIN wishes to thank the journal Nature communications for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Nat. Commun.