header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-150720-4
Huysseune et al., 2014 - Wnt signaling during tooth replacement in zebrafish (Danio rerio): pitfalls and perspectives. Frontiers in Physiology   5:386 Full text @ Front. Physiol.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage Range: Protruding-mouth to Day 5

Fig. 4

Figure 4. Dentition in mbl and apc mutant zebrafish. Dentition in WT (A) and mbl mutants (B) at 5dpf, and WT (C) and apc mutants (D) at 3 dpf. Insets: WT (A) and mbl mutant (B) at 6 dpf, and WT (C) and apc mutant (D) at 2 dpf. Color codes for arrowheads as in Figure 3. Note the complete similarity in tooth pattern between 5 dpf WT (A) and mbl mutants (B), and the substantial developmental delay in 3 dpf apc mutants (D) compared to WT fish (C), as can be observed from the large amount of yolk (y) still present, the thin endodermal layer covering the yolk (black arrowhead), and the absence of cartilage in the neurocranial base flanking the notochord (nc). Ov, otic vesicle. Note that sections are slightly oblique and different sets of teeth are visible on either body side. Scale bars = 50 ┬Ám.

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
apchu745/hu745 standard conditions Protruding-mouth embryo development decreased rate, abnormal
Protruding-mouth head shape, abnormal
Protruding-mouth pharynx immature, abnormal
Protruding-mouth tooth placode agenesis, abnormal
Protruding-mouth yolk increased size, abnormal
axin1tm213/tm213 standard conditions Day 5 eye absent, abnormal
Day 5 forebrain absent, abnormal
Day 5 replacement tooth 4V immature, abnormal
Day 5 replacement tooth 4V present, normal
Day 5 tooth 3V present, normal
Day 5 tooth 4V present, normal
Day 5 tooth 5V present, normal
Acknowledgments:
ZFIN wishes to thank the journal Frontiers in Physiology for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Front. Physiol.