ZFIN ID: ZDB-FIG-150602-50
Jiang et al., 2015 - Functional Loss of Semaphorin 3C and/or Semaphorin 3D and Their Epistatic Interaction with Ret Are Critical to Hirschsprung Disease Liability. American journal of human genetics   96:581-596 Full text @ Am. J. Hum. Genet.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Day 5

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-sema3c standard conditions Day 5 enteric neuron decreased amount, abnormal
Day 5 gut innervation disrupted, abnormal
WT + MO1-sema3c + MO2-ret standard conditions Day 5 enteric neuron decreased amount, abnormal
Day 5 gut innervation disrupted, abnormal
WT + MO2-ret standard conditions Day 5 enteric neuron decreased amount, abnormal
WT + MO2-ret + MO3-sema3d standard conditions Day 5 enteric neuron decreased amount, abnormal
Day 5 gut innervation disrupted, abnormal
WT + MO3-sema3d standard conditions Day 5 enteric neuron decreased amount, abnormal
Day 5 gut innervation disrupted, abnormal
Full text @ Am. J. Hum. Genet.