FIGURE
Fig. 8
- ID
- ZDB-FIG-150331-22
- Publication
- Shao et al., 2009 - Down syndrome critical region protein 5 regulates membrane localization of Wnt receptors, Dishevelled stability and convergent extension in vertebrate embryos
- Other Figures
- All Figure Page
- Back to All Figure Page
Fig. 8
Rescue of Dishevelled stability by dn-caveolin and proteosome inhibitor. Western blot analysis of XDsh-Myc at the shield stage of zebrafish embryos. (A) Absence of effect of dscr5 knockdown on the stability of Wnt11-Myc, XFz7-Myc and endogenous β-Catenin. (B) Dose-dependent effect of dscr5 knockdown on XDsh-Myc stability. (C) XDsh-Myc degradation in embryos injected with gly4ΔC RNA or knyMO. (D) Coexpression of dn-caveolin rescues XDsh-Myc stability in dscr5 morphants. (E) MG132, but not NH4Cl, maintains XDsh-Myc stability in dscr5 knockdown cells. Endogenous JNK was used as a loading control. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Development