ZFIN ID: ZDB-FIG-140521-4
Kanwal et al., 2013 - Deficiency in Hematopoietic Phosphatase Ptpn6/Shp1 Hyperactivates the Innate Immune System and Impairs Control of Bacterial Infections in Zebrafish Embryos. Journal of immunology (Baltimore, Md. : 1950)   190(4):1631-1645 Full text @ J. Immunol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibody:
Fish:
Condition:
Knockdown Reagent:
Anatomical Terms:
Stage Range: Protruding-mouth to Day 5
PHENOTYPE:
Fish:
Condition:
Knockdown Reagent:
Observed In:
Stage Range: Protruding-mouth to Day 5

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
GFP i114Tg control Protruding-mouth neutrophil IHC
Day 5 neutrophil IHC
i114Tg + MO1-ptpn6 chemical treatment: pharmaceutical Protruding-mouth neutrophil IHC
Day 5 neutrophil IHC
i114Tg + MO1-ptpn6 standard conditions Protruding-mouth neutrophil IHC
Day 5 neutrophil IHC
zf113Tg; zf44Tg control Day 5 pars intermedia IFL
zf113Tg; zf44Tg chemical treatment: pharmaceutical Day 5 pars intermedia IFL
zf113Tg; zf44Tg + MO1-ptpn6 chemical treatment: pharmaceutical Day 5 pars intermedia IFL
zf113Tg; zf44Tg + MO1-ptpn6 standard conditions Day 5 pars intermedia IFL
RFP zf113Tg; zf44Tg control Day 5 rostral pars anterior IFL
zf113Tg; zf44Tg chemical treatment: pharmaceutical Day 5 rostral pars anterior IFL
zf113Tg; zf44Tg + MO1-ptpn6 chemical treatment: pharmaceutical Day 5 rostral pars anterior IFL
zf113Tg; zf44Tg + MO1-ptpn6 standard conditions Day 5 rostral pars anterior IFL
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-lcp1 IHC i114Tg control Protruding-mouth leukocyte
IHC Day 5 leukocyte
IHC i114Tg + MO1-ptpn6 chemical treatment: pharmaceutical Protruding-mouth leukocyte
IHC Day 5 leukocyte
IHC i114Tg + MO1-ptpn6 standard conditions Protruding-mouth leukocyte
IHC Day 5 leukocyte
Phenotype Details
Fish Conditions Stage Phenotype
i114Tg + MO1-ptpn6 chemical treatment: pharmaceutical Day 5 inflammatory response increased process quality, abnormal
i114Tg + MO1-ptpn6 chemical treatment: pharmaceutical Day 5 leukocyte accumulation heart anatomical region, abnormal
i114Tg + MO1-ptpn6 standard conditions Protruding-mouth leukocyte accumulation heart anatomical region, abnormal
Full text @ J. Immunol.