FIGURE

Fig. 1

ID

ZDB-FIG-140422-1

Publication

Perathoner et al., 2014 - Bioelectric signaling regulates size in zebrafish fins

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Fig. 1

alf mutants lead to an increase in size of the appendages of adult fish.

(A) alf mutations are dominant and lead to overgrown fins and barbels in the adult. Arrows indicate maxillary barbels; the mutants shown are heterozygous. (B) Segment patterning in the dorsal fin of wild type and heterozygous mutants. Brackets indicate one segment. Although the majority of segments show increased length, several short segments can be seen in the mutants (arrows). (C) Variation in segment length (top) and segment number (bottom) in the longest ray of the dorsal fin of mutants and wild type siblings (wt sib). Fish of similar standard length (SL) (i.e. distance between snout and caudal peduncle) were compared; all cases n = 4; error bars: standard deviation; n.s.: not significant; *: p<0.02, ***: p<0.001. (D) Increased allometric scaling of heterozygous alf fins in development. k = allometric coefficient, Linear regression lines, wt R² = 0.92; alf/+, R² = 0.95; ***: p<0.001. (E) Crosses of sof with alf indicate that there is not epistatic interaction between the two genes. Fin length was normalized with SL.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	kcnk5b^dt30mh/+ kcnk5b^ty86d/+
Observed In:	barbel caudal fin developmental growth fin fin development lepidotrichium segment
Stage:	Adult

Phenotype Detail

Acknowledgments

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